arXiv preprints from January 1, 2026 through September 11, 2026 — 11:21:57 EST
We show an explicit qutrit channel whose private and quantum capacities both vanish, although it is neither antidegradable nor positive under partial transposition (PPT). This resolves two longstanding open problems in quantum information theory: whether zero quantum capacity can occur outside the PPT and antidegradable classes, and...
Fluctuation theorems for work provide universal constraints on nonequilibrium fluctuations, yet their quantum generalizations often rely on externally prescribed classical driving protocols. While for classical systems, fluctuation theorems have been extended to autonomous work, where the dynamics of the work source is subject to the...
We prove the sharp uniform continuity bound for quantum conditional entropy. If two bipartite states are at trace distance at most $δ$ and $d=\dim A$, the optimal dimension-only modulus of continuity is $h_2(δ)+δ\log(d^2-1)$ up to $δ=1-d^{-2}$ and $2\log d$ thereafter, where $h_2$ denotes the binary entropy. When $\dim B\ge d$, this...
We develop a motif-based framework for spatiotemporal chaos in spatial evolutionary games and use it to map the dynamical phase diagram in the payoff plane. Using Boolean linearization of the imitate-the-best rule, we derive analytical instability thresholds for local motifs including invaders, cooperative pairs, stripe interfaces,...
Extreme epidemic risk is controlled by the right tail of the outbreak-size distribution, but this distribution is generally unknown for non-Markovian spreading on networks. Here we determine this distribution by mapping non-Markovian SIR dynamics to an effective Markovian description. We show that arbitrary infection and recovery time...
Functional synapse clusters (FSCs) are synapses with correlated presynaptic activity that are colocalized on the same neuronal dendritic branch. FSCs have been observed after learning in cortical and hippocampal pyramidal neurons. However, previous efforts to ablate FSCs by pharmacologically blocking dendritic nonlinearities to...
Magnetic resonance spectroscopic imaging methods are particularly attractive for chemical engineering applications, including the monitoring of chemical reactions, where a rapid assessment of spatial variations in chemical composition is required. Conventional approaches, such as chemical shift imaging, introduce an additional...
High-dimensional data with sparse structure and spatio-temporal dependence arise in many scientific domains. We develop a Bayesian feature-extraction framework for spatio-temporal settings that employs Gaussian and Diffused-gamma priors to induce structured sparsity. The modeling framework specifies a general likelihood via Bregman...
Resting-state functional connectivity (FC) is altered in Alzheimer's disease (AD), widely regarded as a distributed network process; whether its FC signature reduces to a few focal sites has not been tested causally, a question central to targeted neuromodulation. We fit subject-specific, cross-subject-identifiable reservoir-computing...
Large ecosystems balance competition and cooperation, yet standard generalized Lotka--Volterra models make mutualism destabilizing by amplifying disorder and driving unbounded growth. We show that Monod-like saturation resolves this paradox: dynamical mean-field theory and random-matrix analysis reveal a broader stable phase and...
Wind plays a crucial role in changing prey defense strategy and predation efficiency. We develop and analyze a prey-predator model that incorporates wind driven environmental effects, prey group defense, and an additional food strategy for the predator. Wind intensity is assumed to modulate predation efficiency, while prey aggregation...
Objective. To develop and evaluate an adaptive electrode-selection method for tracking non-stationary spontaneous activity during long-term high-density microelectrode array (HD-MEA) recordings under a fixed channel budget. Approach. We formulated electrode allocation as a sequential subset-selection problem and used a discounted...
Complex networked systems are prevalent in biology, engineering, and the social sciences, yet their high-dimensional, nonlinear dynamics pose major challenges for analysis and prediction. A mathematically rigorous route to simplification is to represent system behavior on a low-dimensional, smooth invariant manifold known as a...
The exponential growth of genomic data, particularly for microbes, has made pangenomic approaches a gold standard for large-scale comparative genomics. By capturing the full genomic diversity of a species rather than relying on a single reference, pangenomics has transformed microbial genomics, revealing the adaptive potential of...
Cell type standardization plays a central role in integrating biological knowledge across single-cell studies. While standardized resources (e.g., Cell Ontology, Nomenclature Frameworks) provide unified vocabularies of cell populations, scientific publications and public datasets continue to use heterogeneous study-specific labels,...
Large language model research agents can connect literature retrieval, analysis code, and manuscript preparation, but coherent output does not establish scientific validity. We developed Plato-Bio, a biology-routed extension of the open Plato/Denario architecture that couples explicit workflow states with provenance records, citation...
A conversational AI that cannot tell its own output from what a user said will treat its own mistakes as user-provided facts. In humans, this capacity is called reality monitoring, and its failures are linked to hallucinations, delusions, and confabulation, yet whether LLMs possess it remains untested. Here we show, across two...
Mechanical instabilities provide a general design principle for shaping developing organs and engineering soft materials. However, in slender structures, simple elastic buckling tends to erase rather than preserve shape complexity: structures relax to the simplest possible shape, erasing finer detail. Living systems nonetheless build...
We are studying a new regulator of microtubule homeostasis, wdA, in the fungus Aspergillus nidulans. Mutations in wdA confer cold-sensitive lethal mitotic catastrophe, suggesting an important role in microtubule-based processes. Previous genetic studies showed that deletion of TBCA causes a near-lethal phenotype that is suppressed by...
Visual prostheses require users to interpret sparse and distorted artificial percepts through active visual search. We developed an EEG-guided neuroadaptive training platform for simulated prosthetic vision in immersive virtual reality and evaluated its feasibility in a sham-controlled object-localization task. Twenty-two sighted...
Identifying therapeutic target genes from single-cell RNA sequencing (scRNA-seq) data remains a fundamental challenge in translational biology. Unlike bulk assays, scRNA-seq captures heterogeneous cellular states and rare subpopulations, but this same heterogeneity makes target discovery highly sensitive to analytical choices...
This paper presents a robust mathematical framework for quantifying antiproliferative effects from noisy in vitro cell viability experiments. The methodology is demonstrated using crystal violet assay measurements of quinolinic acid-induced growth inhibition in B16-F10 murine melanoma, RAW264.7 macrophage, and HaCaT keratinocyte cells...
We consider the spatial spread of epidemic into an unstable, healthy state. When the transmission rate depends on the fraction of infected, the propagating pulse of infection can be either a pulled front or a pushed front. We determined the phase space of parameters for the pulled and pushed regions both by numerically solving the...
The rapid evolution of generative models has unlocked new potentials in protein binder design, a pivotal task in structural biology, by facilitating end-to-end generation via joint sequence-structure modeling or hallucination. However, existing approaches are predominantly implemented under a single-target, single-state assumption,...
Specific mixing or demixing of molecular species is a characteristic feature of condensed intracellular membraneless compartments. How sequence patterns of intrinsically disordered proteins (IDPs) fundamentally impact subcompartmentalization of biomolecular condensates and their role in buffering against concentration fluctuations are...