arXiv preprints from January 1, 2026 through September 13, 2026 — 18:24:01 EST
Identifying protein targets for small molecules, or reverse screening, is essential for understanding drug action, guiding compound repurposing, predicting off-target effects, and elucidating the molecular mechanisms of bioactive compounds. Despite its critical role, reverse screening remains challenging because accurately capturing...
This study aims to investigate the relationship between the spatial-temporal evolution of shock properties and the longitudinal dependence of SEP intensities and spectra. The shock parameters, including the normal speed, oblique angles, compression ratio, and Alfven Mach number, were derived by combining a steady-state solar-wind...
The orbital angular momentum (OAM) of light provides an unbounded set of orthogonal modes for ultrahigh-capacity optical information processing. However, current OAM detection schemes typically rely on light interference or diffraction, which require bulky optical components and pose a major obstacle to on-chip integration. Here, we...
Clinical Decision Support Systems (CDSSs) provide reasoning and inquiry guidance for physicians, yet they face notable challenges, including high maintenance costs and low generalization capability. Recently, Large Language Models (LLMs) have been widely adopted in healthcare due to their extensive knowledge reserves, retrieval, and...
Law enforcement authorities are increasingly interested in 3D modelling for virtual crime scene reconstruction, enabling offline analysis without the cost and contamination risk of on-site investigation. Past work has demonstrated spatial relationships through static modelling but validating the sequence of events in dynamic scenarios...
The inherent non-convexity of poriferous surfaces typically entraps agents in local minima and complicates workload distribution. To resolve this, we propose a distributed diffeomorphic coverage control framework for the multi-agent system (MAS) in such surfaces. First, we establish a distributed poly-annulus conformal mapping that...
Existing dynamic Theory of Mind (ToM) benchmarks mostly place language models in a passive role: the model reads a sequence of connected scenarios and reports what people believe, feel, intend, and do as these states change. In real social interaction, ToM is also used for action: a speaker plans what to say in order to shift another...
We study optimal dynamic persuasion in a bandit experimentation model where a principal, unlike in standard settings, has a single-peaked preference over the agent's stopping time. This non-monotonic preference arises because maximizing the agent's effort is not always in the principal's best interest, as it may lead to a dead end....
Agentic artificial intelligence (AI) is an AI paradigm that can perceive the environment, reason over observations, and execute actions to achieve specific goals. Task-oriented communication supports agentic AI by transmitting only the task-related information instead of full raw data in order to reduce the bandwidth requirement. In...
The linear memory growth of the KV cache poses a significant bottleneck for LLM inference in long-context tasks. Existing static compression methods often fail to preserve globally important information. Although recent dynamic retrieval approaches attempt to address this issue, they typically suffer from coarse-grained caching...
Diffusion transformers (DiTs) have emerged as a powerful architecture for high-fidelity image generation, yet the quadratic cost of self-attention poses a major scalability bottleneck. To address this, linear attention mechanisms have been adopted to reduce computational cost; unfortunately, the resulting linear diffusion transformers...
The rise of reasoning models necessitates large-scale verifiable data, for which programming tasks serve as an ideal source. However, while competitive programming platforms provide abundant problems and solutions, high-quality test cases for verification remain scarce. Existing approaches attempt to synthesize test cases using Large...
The Open-Radio Access Network (O-RAN) integrates numerous software components in a cloud-like deployment, opening the radio access network to previously unconsidered security threats. With the ever-evolving threat landscape, integrating security practices through a DevSecOps approach is essential for fast and secure releases. Current...
With the growing applications of the Internet of Things (IoT), a major challenge is to ensure continuous connectivity while providing prioritized access. In dense IoT scenarios, synchronization may be disrupted either by the movement of nodes away from base stations or by the unavailability of reliable Global Navigation Satellite...
This letter presents ShuffleFAC, a lightweight acoustic model for ship-radiated sound classification in resource-constrained maritime monitoring systems. ShuffleFAC integrates Frequency-Aware convolution into an efficiency-oriented backbone using separable convolution, point-wise group convolution, and channel shuffle, enabling...
The climate system's nonlinear dynamics is influenced by various external forcings and internal feedbacks that can give rise to regional and even global tipping points that may lead to significant and potentially irreversible changes. Paleoclimatic records reveal that Earth's climate has shifted between distinct equlibria, including a...
Active learning (AL) has the potential to drastically reduce annotation costs in 3D biomedical image segmentation, where expert labeling of volumetric data is both time-consuming and expensive. Yet, existing AL methods are unable to consistently outperform improved random sampling baselines adapted to 3D data, leaving the field...
Accurate simulation of brain deformation is a key component for developing realistic, interactive neurosurgical simulators, as complex nonlinear deformations must be captured to ensure realistic tool-tissue interactions. However, traditional numerical solvers often fall short in meeting real-time performance requirements. To overcome...
Modern macroeconomic monetary theory suggests that the labor share of income has effectively become a core macroe-conomic parameter anchored by top policymakers through Open Market Operations (OMO). However, the setting of this parameter remains a subject of intense economic debate. This paper provides a detailed summary of these...
In a high temperature regime where $βN \to 2c$, the empirical distribution of the eigenvalues of Gaussian beta ensembles, beta Laguerre ensembles and beta Jacobi ensembles converges to a limiting measure which is related to associated Hermite polynomials, associated Laguerre polynomials and associated Jacobi polynomials, respectively....
Nonlinear manifold learning (ML) based reduced-order models (ROMs) can substantially improve the quality of nonlinear flow-field modeling. However, noise and the lack of physical information often distort the dimensionality-reduction process, reducing the robustness and accuracy of flow-field prediction. To address this problem, we...
Karapetrović conjectured that the norm of the Hilbert matrix operator on the Bergman space $A^p_α$ is equal to $π/\sin((2+α)π/p)$ when $-1<α<p-2$. In this paper, we provide a proof of this conjecture for $0\leq α\leq \frac{6p^3-29p^2+17p-2+2p\sqrt{6p^2-11p+4}}{(3p-1)^2}$, and this range of $α$ improves the best known result when...
Orchestrated multi-agent systems represent the next stage in the evolution of artificial intelligence, where autonomous agents collaborate through structured coordination and communication to achieve complex, shared objectives. This paper consolidates and formalizes the technical composition of such systems, presenting a unified...
The transcription of historical documents written in Latin in XV and XVI centuries has special challenges as it must maintain the characters and special symbols that have distinct meanings to ensure that historical texts retain their original style and significance. This work proposes a pipeline for the transcription of historical...
The ALMA survey to Resolve exoKuiper belt Substructures (ARKS) was recently completed to cover the lack of high-resolution observations of debris discs and to investigate the prevalence of substructures such as radial gaps and rings in a sample of 24 discs. This study characterises the radial structure of debris discs in the ARKS...