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arXiv preprints from January 1, 2026 through September 7, 2026 — 06:50:56 EST

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Posted in q-bio.NC · 2026-08-29 · Wenjun Xia, Yan Xu, Zhengdi Zhang

Front-end and Back-end Computational Modeling of 40-Hz Auditory Steady-State Response Abnormalities in Schizophrenia

40-Hz ASSR is reduced in schizophrenia, but it is unclear if this reflects altered auditory input or cortical E/I dynamics. We hypothesized that similar group differences could arise via distinct model mechanisms. EEG gamma% and ITPC from 21 HC and 21 SCZ constrained an auditory front-end coupled to a Wilson-Cowan E/I model. We...

💬 0 commentsarXiv:2608.29104v1PDF
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Posted in cs.AI · 2026-08-29 · Runyu Guan, Dehao Wu, Qiqi Xie, Yang Li, Haohan Wang

Agentic AI uncovers conserved cross-tissue protein co-abundance programs inaccessible to single-dataset analysis

Protein co-abundance clusters preserved across tissues can reveal shared disease mechanisms and candidate therapeutic targets, particularly when proteins implicated in organ-confined diseases converge in peripheral or accessible tissues. However, previous cross-tissue studies have focused on biologically pre-selected tissue pairs,...

💬 0 commentsarXiv:2608.28990v1PDF
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Posted in q-bio.NC · 2026-08-28 · Seyed Majid Razavi, Saeed Tajik Hesarkuchak, Triet M. Tran, Mehdi Zaeifi, Amirhossein Arezoumand, Farnaz Zamani Esfahlani, Jason A. Oliver, Sina Khanmohammadi

Structurally Informed Connectivity Disruptions in Cocaine Use Disorder

Cocaine Use Disorder (CUD) is associated with widespread alterations in large-scale functional brain networks, yet the mechanisms contributing to these changes and their relationship to clinical and cognitive outcomes remain poorly understood. To address this gap, we introduce a framework to extract structurally informed dynamic...

💬 0 commentsarXiv:2608.28892v1PDF
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Posted in q-bio.GN · 2026-08-28 · Calvin McCarter

Confounder-Aware Feature Correction for Single-Cell Batch Integration

Batch integration is a central preprocessing step in single-cell genomics, where datasets collected across experiments, donors, and protocols must be combined despite pervasive technical batch effects. The leading integration methods produce a shared low-dimensional embedding, which discards the corrected gene-expression values that...

💬 0 commentsarXiv:2608.28849v1PDF
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Posted in q-bio.BM · 2026-08-28 · Riku Itsuji, Yuanhao Wang, Xingjian Li, Seonghui Min, Hideo Saito, Min Xu

Reconstruction-Aware Cryo-EM Particle Picking

Cryo-electron microscopy (cryo-EM) determines the structures of proteins and macromolecular assemblies at near-atomic resolution, and the final 3D reconstruction depends on extracting a clean particle stack from noisy micrographs. This extraction decomposes into three sub-tasks, namely particle picking, contamination removal, and 2D...

💬 0 commentsarXiv:2608.28838v1PDF
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Posted in q-bio.QM · 2026-08-28 · Riku Itsuji, Rintaro Otsubo, Ryo Fujii, Xingjian Li, Xiaolong Wu, Hideo Saito, Min Xu

CryoAnomaly: Few-Shot Cryo-EM Particle Picking via Anomaly-Guided Hard Negative Suppression

Cryo-electron microscopy (cryo-EM) is crucial for analyzing 3D biological structures, in which automated particle picking is essential for the workflow. However, fully supervised methods require extensive manual annotations. While few-shot learning offers a potential solution, existing approaches struggle to handle the diverse...

💬 0 commentsarXiv:2608.28817v1PDF
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Posted in q-bio.OT · 2026-08-28 · Mavia Anjum, Gwendolyn D. Bart

Geochemical Hazard Assessment of Martian Regolith for Future Human Exploration

As human missions to Mars move from concept to planning to reality, a systematic quantitative health risk assessment of martian regolith exposure has become critically important. This study presents a comprehensive multi-element, multi-pathway health hazard analysis of martian regolith for a 70 kg adult astronaut on an 18-month...

💬 0 commentsarXiv:2608.28805v1PDF
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Posted in q-bio.QM · 2026-08-28 · Jonathan A. Levine, Melissa Pathil, Samuel Nitz, Olga Lyudovyk, Benjamin D. Greenbaum

FoldKit: A Python library for efficient storage and retrieval of co-folding predictions

AlphaFold 3 (AF3) enables structure prediction of biomolecular complexes through co-folding multiple interacting molecules, making it increasingly useful for de novo protein design and for large-scale studies of protein-protein, protein-peptide, and other biomolecular interactions. However, systematic co-folding experiments can...

💬 0 commentsarXiv:2608.28788v1PDF
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Posted in q-bio.NC · 2026-08-28 · Alessandro T. Gifford, Pablo Oyarzo, Anne W. Zonneveld, Christina Sartzetaki, Iris I. A. Groen, Radoslaw M. Cichy

A large dataset of human EEG responses to short naturalistic videos for studying dynamic visual event processing

Vision neuroscience has experienced a surge in the collection and use of large-scale datasets of brain responses to naturalistic images. However, static images lack the temporal dimension essential for understanding how vision is solved in the brain during dynamic real life settings. To facilitate the study of the neural correlates of...

💬 0 commentsarXiv:2608.28768v1PDF
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Posted in cs.SE · 2026-08-31 · Yisen Xi

Auditing Anonymous AI Models: A Four-Stage Protocol for Black-Box Identity Verification

The 2025--2026 AI market has seen a wave of stealth releases: frontier models launched anonymously on developer platforms under codenames. For their users, identity determines data-handling terms, supply-chain risk, and capability expectations. No validated methodology exists for black-box identity verification of anonymous models:...

💬 0 commentsarXiv:2608.31142v1PDF
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Posted in cs.IT · 2026-08-31 · Irtiza Hasan, Ahmed Arafa

Semantic Freshness Optimal Sampling and Transmission for Gossiping Receivers

We study the optimal joint sampling and transmission policy for a transmitter communicating with two gossiping receivers that share information with each other, with the objective of tracking a source under the Version Age of Information (VAoI) metric. The transmitter can observe source-version changes, but it has to pay a sampling...

💬 0 commentsarXiv:2608.31140v1PDF
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Posted in cs.CL · 2026-08-31 · Riya Ahuja, Tim Kacprowski, Roya Shiasi Sardoabi

Configurable Semantic Chunking for Biomedical Information Extraction in Retrieval-Augmented Generation

BioMedRAG introduced retrieval-augmented generation with a learned chunk scorer for biomedical information extraction. However, it relies on fixed-size chunking which can fragment semantic evidence. We propose a configurable semantic chunking framework that addresses this limitation by combining entity-preserving windows,...

💬 0 commentsarXiv:2608.31139v1PDF
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Posted in cs.AI · 2026-08-31 · Hamed Babaei Giglou, Sören Auer, Peio Popov, Mahsa Sanaei, Jennifer D'Souza

OntoAligner-Ensemble: Voting-Based Fusion across Heterogeneous Ontology Alignment Techniques

Ontology alignment (OA) has evolved through several methodological paradigms, ranging from lexical and structural aligners to knowledge graph embedding (KGE) models and, more recently, Large Language Model (LLM)-based approaches. Although modern OA frameworks provide unified ecosystems for deploying these heterogeneous aligners,...

💬 0 commentsarXiv:2608.31137v1PDF
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Posted in stat.ML · 2026-08-31 · Nan Zheng, Hoi Yiu Cheung, Vibhu Sharma, James T. Thorson, Noel G. Cadigan

Implementing neural network mixed-effects models in Template Model Builder (TMB)

Neural network mixed-effects models (NMMs) have gained traction by combining the strong representation and predictive power of artificial neural networks with the capacity of mixed-effects modeling to capture complex correlation structures. However, existing estimation approaches rely heavily on manual derivations of objective...

💬 0 commentsarXiv:2608.31133v1PDF
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Posted in cs.CL · 2026-08-31 · Yung Wei Shueh, Zhi-Jie Chen, Chia-Hsuan Hsu, Hsin-Ling Hsu, Donghua Zhang, Chenwei Wu, Jun-En Ding, Tongze Zhang, Shihao Yang, Pengfei Hu, Fang-Ming Hung, Feng Liu

DIASENTINEL: An Auditable Multi-Agent System for Guideline-Grounded Diabetes Risk Screening

Large language models (LLMs) offer promising clinical decision support but remain vulnerable to hallucinated facts, unsupported recommendations, and citation errors. We present DIASENTINEL, a fully on-premise multi-agent system for one-year type 2 diabetes mellitus (T2DM) risk screening and guideline-grounded report generation from...

💬 0 commentsarXiv:2608.31128v1PDF
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Posted in cs.GT · 2026-08-31 · Benjamin Cookson, Nisarg Shah

Constrained Fair Allocations via Partition Matroid Reductions

We study fair allocation of indivisible goods under additive valuations and matroid constraints. A challenging open question is whether a complete and feasible envy-free up to one good (EF1) allocation exists under every matroid that admits a complete and feasible allocation. The state-of-the-art result by Biswas and Barman [2018]...

💬 0 commentsarXiv:2608.31121v1PDF
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Posted in cs.CL · 2026-08-31 · Yuhan Wang, Zhengxi Lu, Yuchen Yan, Kaitao Song, Wenqi Zhang, Weiming Lu, Jun Xiao, Yueting Zhuang, Yongliang Shen

PaperGym: Rubric-Centered Evolution for Research-Plan Generation

Research planning is the decisive capability of AI scientists. Yet a research plan admits no verifiable answer, so reinforcement learning lacks the environment it requires: tasks paired with a critic. Rubrics extracted from scientific papers can supply the critic. Existing pipelines, however, draw the question and the criteria from...

💬 0 commentsarXiv:2608.31119v1PDF
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Posted in cs.AI · 2026-08-31 · Hamed Babaei Giglou, Sören Auer, Jennifer D'Souza

When Does Bigger Help? A Controlled Study of LLM Scale for Ontology Learning

The effect of Large Language Model (LLM) scale on ontology learning (OL) performance remains insufficiently characterized. We present a controlled evaluation of 13 models spanning dense and Mixture-of-Experts variants from the Qwen3.5 and Qwen3.6 lineages, together with proprietary GPT release variants, using the OntoLearner...

💬 0 commentsarXiv:2608.31118v1PDF
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Posted in quant-ph · 2026-08-31 · Snehal Raj, Natansh Mathur, Alejandro Perdomo-Ortiz

"Train classical, deploy quantum" requires rethinking generalization

Generative models have become central across science and industry, from image and text synthesis to the design of molecules and materials. Quantum generative models are considered one of the most promising applications for quantum computers, since a quantum circuit naturally produces samples from the distribution it encodes, and for...

💬 0 commentsarXiv:2608.31117v1PDF
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Posted in cs.HC · 2026-08-31 · Mohammad Abolnejadian, Matthew Brehmer

InsightToast: Proactive Information Retrieval & Glanceable Visualization in the Side Channel of Data-Rich Meetings

Missing institutional context during meetings can impede effective participation. Retrieving relevant information, often scattered across heterogeneous internal and external sources, requires costly task-switching that disrupts both individual focus and collective conversational flow, particularly detrimental during cognitively...

💬 0 commentsarXiv:2608.31115v1PDF
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Posted in cs.CV · 2026-08-31 · Pradyumn Goyal, Yizhak Ben-Shabat, Hsueh-Ti Derek Liu, Haomiao Jiang, Snehasish Mukherjee, Kyle Spence, Mark Stauber, Evangelos Kalogerakis, Yunze Zeng

BLARM: Animating 3D Objects from Video via Blending Latent Rigid Motion Primitives

We introduce BLARM, a feed-forward method for video-driven 3D mesh animation. Given a monocular video and a static object mesh, BLARM predicts a temporally coherent animated mesh whose motion follows the video. Rather than relying on explicit rigs or directly regressing high-dimensional vertex motion, we represent animation using a...

💬 0 commentsarXiv:2608.31113v1PDF
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Posted in quant-ph · 2026-08-31 · Andrea Coladangelo, Dakshita Khurana, Saachi Mutreja, Bhaskar Roberts, Joseph Slote, Avishay Tal

Unconditional Certified Randomness without Structure

We obtain a certified randomness protocol in the quantum random oracle model. The protocol is non-interactive and publicly verifiable with a classical verifier, and is based on Yamakawa and Zhandry's proof of quantumness [JACM'24]. We prove unconditional security of this protocol against adversaries making subexponentially-many...

💬 0 commentsarXiv:2608.31112v1PDF
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Posted in cs.CL · 2026-08-31 · Yuhao Wu, Jingyuan Zhang, Jiajun Shi, Yuxuan Zhang, Xinping Lei, Junting Zhou, Zexuan Wang, Yuchen Wu, Huan Zhou, Duo Wang, Yinzhu Piao, Yongchang Peng, Yunfeng Shi, Jin Chen, Zuo Wang, Jinkai Liu, Jiaheng Liu, Wenxuan Zhang, Shen Yan, Wenhao Huang, Ge Zhang

Aspire: Can Models Self-Evolve from Vague Goals?

Many important forms of human learning begin with a vague goal, such as "become a better physicist" or "improve at research." Learners must interpret the goal, identify capability gaps, decide how to learn, and determine whether they have actually improved. In contrast, existing work on LLM self-evolution typically begins with tasks...

💬 0 commentsarXiv:2608.31111v1PDF
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Posted in cs.LG · 2026-08-31 · Ahmed El Kady, Aravind Narayanan, Rehana Noorani, Yani Ioannou, Shaina Raza

Stress-Testing Efficient Responsible-AI Evaluation: When Compute Savings Change Benchmark Conclusions

Efficient evaluation changes the protocol used to support claims about model behavior, yet it is rarely tested whether those claims remain stable after the evaluation itself is made cheaper. We stress-test conclusion robustness in responsible-AI benchmarking by evaluating three dense and mixture-of-experts models on BBQ and BBQ-V...

💬 0 commentsarXiv:2608.31108v1PDF
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Posted in cs.CV · 2026-08-31 · Lucas Wojcik, Gabriel E. Lima, Sergio M. Silva, Eduil Nascimento, David Menotti

VeriCam: A Verification Baseline for the Classification of Unknown Data

The advent of foundation models have enabled a new era in zero-shot classification. Yet, key challenges persist. Despite their impressive generalization power that leverages the immense pre-training knowledge, both foundation models for image and text as well as vision-text hybrids lack the representational power needed for...

💬 0 commentsarXiv:2608.31107v1PDF